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Article

TERTmonitor Efficacy and Performance in Detecting Mutations by Droplet Digital PCR.

Genes - 31 Oct 2024

Bessa-Gonçalves Mafalda, Brás João Paulo, Jesus Tito Teles, Prazeres Hugo, Soares Paula, Vinagre João

Abstract excerpt

BACKGROUND: The screening of TERT promoter (TERTp) mutations is essential in cancer research and diagnostics, due to its prevalence in tumours associated with low self-renewal rates. TERTmonitor is a diagnosis kit primarily designed for real-time qPCR qualitative detection of -124C>T and -146C>T TERTp mutations, which are highly prevalent in several malignancies, particularly in bladder carcinoma. OBJECTIVE: This...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39596624
DOI: 10.3390/genes15111424
PMCID: PMC11594489

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