Digital PCR-Based Uromonitor for Molecular Detection of Bladder Cancer: A Multicenter Validation Study Comparing Quantitative PCR and Urine Cytology.

doi:10.1016/j.clgc.2026.102554

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Digital PCR-Based Uromonitor for Molecular Detection of Bladder Cancer: A Multicenter Validation Study Comparing Quantitative PCR and Urine Cytology.

Clinical genitourinary cancer - 1 Jun 2026

Kravchuk Anton, Garzaro Julio Ruben Rodas, Wirtz Ralph, Wolff Ingmar, Koch Stefan, Schlomm Thorsten, Rabien Anja, Meisl Christina, Rong Dezhi, Brás João Paulo, Vinagre João, Otto Thomas, Barski Dimitri, Gössl Andreas, Siepmann Stephan, Gilfrich Christian, Brookman-May Sabine, Ecke Thorsten, May Matthias

Abstract excerpt

INTRODUCTION: Non-invasive urine-based diagnostics for urothelial carcinoma of the bladder remain limited by suboptimal sensitivity. We validated a digital polymerase chain reaction (dPCR) UromonitorⓇ assay in a multicentre setting and compared it with an earlier quantitative polymerase chain reaction (qPCR) version and urine cytology. PATIENTS AND METHODS: We analyzed 239 archived urine samples from a...

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PMID: 42049549
DOI: 10.1016/j.clgc.2026.102554

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FGFR3
TERT

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