Article

Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease: Insights into Pathophysiology and Treatment

2025-03-17

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily marked by cognitive decline and memory loss. Oxidative stress (OS) has emerged as a critical factor in AD pathogenesis, contributing to hallmark features such as amyloid-β (Aβ) plaque formation, tau hyperphosphorylation, and synaptic dysfunction. This review delves into the complex mechanisms driving reactive oxygen species (ROS) p...

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Literature Corpus work: f0cb8253-9734-5cd0-ad02-7e2dc2529dc4
DOI: 10.20944/preprints202408.1375.v2

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