Article
MUC5B Genotype and Other Common Variants Are Associated with Computational Imaging Features of Usual Interstitial Pneumonia.
Annals of the American Thoracic Society - 1 Apr 2025
Blumhagen Rachel Z, Humphries Stephen M, Peljto Anna L, Lynch David A, Cardwell Jonathan, Bang Tami J, Teague Shawn D, Sigakis Christopher, Walts Avram D, Puthenvedu Deepa, Wolters Paul J, Blackwell Timothy S, Kropski Jonathan A, Brown Kevin K, Schwarz Marvin I, Yang Ivana V, Steele Mark P, Schwartz David A, Lee Joyce S
Abstract excerpt
Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex and heterogeneous disease. Given this, we reasoned that differences in genetic profiles may be associated with unique clinical and radiologic features. Computational image analysis, sometimes referred to as radiomics, provides objective, quantitative assessments of radiologic features in subjects with pulmonary fibrosis. Objectives: To determine if the...
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