Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical Utility of a Novel Triplex Digital PCR Assay for Clone Monitoring in Sequential and Relapsed Pediatric B-Cell Acute Lymphoblastic Leukemia Patients.

Pediatric blood & cancer - 1 Feb 2025

Bhatia Prateek, Thakur Rozy, Sreedharanunni Sreejesh, Singh Minu, Malhotra Meenakshi, Arora Swati, George Ashish, Trehan Amita

Abstract excerpt

INTRODUCTION: Digital polymerase chain reaction (PCR) studies for clonal disease monitoring in B-acute lymphoblastic leukemia patients are currently limited due to the heterogeneous nature of mutations, which limit cost-effective assay designs. MATERIALS AND METHODS: In this study, 70 samples (14 relapse and 56 sequential therapy samples) were tested for 13 recurrent mutations identified on deep sequencing in our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Infant

Share to Multiplex Polymerase Chain Reaction

Share to Neoplasm Recurrence, Local

Share to Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Share to Prognosis

Source

Identifiers

PMID: 39582113
DOI: 10.1002/pbc.31443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical Utility of a Novel Triplex Digital PCR Assay for Clone Monitoring in Sequential and Relapsed Pediatric B-Cell Acute Lymphoblastic Leukemia Patients.PMID 39582113Read ↗

Clinical utility of a novel triplex digital PCR assay for clone monitoring in sequential and relapsed pediatric B-cell acute lymphoblastic leukemia patientsSemantic proximity Read ↗

Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia.Semantic proximity Read ↗

Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia.Semantic proximity Read ↗

Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute LeukemiaSemantic proximity Read ↗

Early detection and better outcomes: molecular approaches in pediatric hematologic malignancies – a reviewSemantic proximity Read ↗

Molecular monitoring in NUP214-ABL-positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy.Semantic proximity Read ↗

Molecular Monitoring of Lymphomas.Semantic proximity Read ↗

Diplotype analysis of NUDT15 using digital PCR in pediatric acute lymphoblastic leukemiaSemantic proximity Read ↗

SJPedPanel: A pan-cancer gene panel for childhood malignanciesSemantic proximity Read ↗

Molecular characterization and biomarker identification in paediatric B-cell acute lymphoblastic leukaemia.Semantic proximity Read ↗

Single‐cell DNA and surface protein characterization of high hyperdiploid acute lymphoblastic leukemia at diagnosis and during treatmentSemantic proximity Read ↗

Feasibility of monitoring peripheral blood to detect emerging clones in children with acute lymphoblastic leukemia†.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.