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Article

MAFB-mediated CEBPA regulated human urothelium growth through Wnt/β-catenin signaling pathway

13 Sept 2024

Abstract excerpt

MAFB is essential for regulating male-type urethral differentiation, and especially, its variation can contribute to hypospadias in mice. However, the potential mechanism is still unclear. Here we observed that the basic leucine zipper (bZIP) transcription factor MAFB and CCAAT/enhancer-binding protein alpha (CEBPA) could promote human urothelium SV-HUC-1 growth. Moreover, MAFB and CEBPA expression were reduced...

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PMID: 39569391
DOI: 10.1016/j.gendis.2024.101432

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