Article
Association between the variations in metabolic pathways and oral cancer risk: results from a Pakistani case-control study.
Molecular biology reports - 19 Nov 2024
Shabbir Arifa, Rashid Muhammad Usman, Awad Ezzat M, Naeemi Humaira, Barisani-Asenbauer Talin, Malkani Naila
Abstract excerpt
BACKGROUND: Oral cancer (OC) is a significant global health concern, with Pakistan ranking 5th worldwide in OC incidence. Given the poor prognosis, early detection of at-risk individuals is crucial. Genetic factors, particularly single nucleotide polymorphisms (SNPs) in metabolic genes, may influence OC susceptibility. This study investigated the association between SNPs in CYP1A1, COX2, SOD2, and HIF1a genes and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
