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Multi-omics analysis reveals cuproptosis and mitochondria-based signature for assessing prognosis and immune landscape in osteosarcoma

4 Jan 2024

Abstract excerpt

Background: Osteosarcoma (OSA), the most common primary mesenchymal bone tumor, is a health threat to children and adolescents with a dismal prognosis. While cuproptosis and mitochondria dysfunction have been demonstrated to exert a crucial role in tumor progression and development, the mechanisms by which they are regulated in OSA still await clarification. Methods: Two independent OSA cohorts containing...

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PMID: 38250070
DOI: 10.3389/fimmu.2023.1280945

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