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Identifying genetic targets in clinical subtypes of Parkinson’s disease for optimizing pharmacological treatment strategies

18 Nov 2024

Abstract excerpt

The heterogeneity of Parkinson's disease (PD) has been recognized in clinical, with patients categorized into distinct subsets based on motor phenotype, such as tremor-dominant PD (TD), postural instability and gait difficulty-dominant PD (PIGD) and mixed PD (Mix). Despite this categorization, the underlying mechanisms of this heterogeneity remain poorly understood, and there is no personalized effective...

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PMID: 39551798
DOI: 10.1038/s41392-024-02020-x

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