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Article

Exploring genetic associations between immune cells and hypertensive disorder of pregnancy using Mendelian randomization.

BMC pregnancy and childbirth - 15 Nov 2024

Liu Jingting, Dong Yijun, Zhou Yawei, Wang Wendi, Li Yan, Pei Jianying

Abstract excerpt

BACKGROUND: Observational epidemiological studies suggested that immunological dysregulation and inflammation play a significant role in the placental and renal dysfunction that leads to maternal hypertension. The immunophenotypes' possible causalities with hypertensive disease of pregnancy remain ambiguous. We performed two-sample Mendelian randomization (MR) analyses to comprehensively investigate the causal...

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Identifiers

PMID: 39548401
DOI: 10.1186/s12884-024-06950-w
PMCID: PMC11566496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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