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Article

Circulating immune cells and apolipoprotein A mediation: a Mendelian randomization study on hypertensive disorder of pregnancy.

Frontiers in immunology - 1 Jan 2024

Liu Jingting, Zhou Yawei, Dong Yijun, Wang Wendi, Li Yan, Pei Jianying

Abstract excerpt

Background: Studies using observational epidemiology have indicated that inflammation and immunological dysregulation are important contributors to placental and renal failure, which ultimately results in maternal hypertension. The potential causal relationships between the immunophenotypes and hypertensive disorder of pregnancy (HDP) are yet unclear. Methods: We conducted two-sample Mendelian randomization (MR)...

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Apolipoproteins A
Biomarkers
Genome-Wide Association Study
Hypertension, Pregnancy-Induced
Immunophenotyping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39355245
DOI: 10.3389/fimmu.2024.1438680
PMCID: PMC11442235

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