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The genetic relationships between immune cell traits, circulating inflammatory proteins and preeclampsia/eclampsia.

Frontiers in immunology - 1 Jan 2024

Liu Yu, Zhang Yuliang, Du Lili, Chen Dunjin

Abstract excerpt

Objectives: Preeclampsia/eclampsia (PE), a critical complication during pregnancy, has been suggested to correlate with immune cell phenotypes and levels of circulating inflammatory proteins. Our study aimed to employ a two-sample mendelian randomization (MR) analysis to assess the potential causal effects of immune cell phenotypes and circulating inflammatory proteins on the onset of PE. Methods: We utilized...

Topics

Humans
Female
Pre-Eclampsia
Pregnancy
Genome-Wide Association Study
Genetic Predisposition to Disease
Mendelian Randomization Analysis
Phenotype
Polymorphism, Single Nucleotide
Biomarkers
Adult

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Inflammation

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Identifiers

PMID: 38873604
DOI: 10.3389/fimmu.2024.1389843
PMCID: PMC11170637

Genes

CD4
CD33
CD14
CD24
CD27
CD28
CD38
CD80
STAM

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