Article
Risk allele of gene variant rs6584389 is associated with increased intima-media thickness in patients with type 2 diabetes.
VASA. Zeitschrift fur Gefasskrankheiten - 1 Jun 2018
Kozarova Miriam, Malachovska Zuzana, Zidzik Jozef, Javorsky Martin, Demkova Katarina, Habalova Viera, Tkac Ivan
Abstract excerpt
BACKGROUND: Genome-wide association studies identified several gene variants associated with peripheral arterial disease (PAD). Among them, rs6584389 A>C was significantly associated with PAD defined by decreased ankle-brachial index (ABI). The aim of this study was to investigate whether the rs6584389 variant is also associated with the earlier stages of atherosclerosis assessed by intima-media thickness (IMT)...
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