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A higher JAK2V617F allele burden may be a risk factor for hemorrhagic events in younger patients with polycythemia vera.

Hematology (Amsterdam, Netherlands) - 1 Dec 2024

Furuya Chiho, Hashimoto Yoshinori, Morishita Soji, Fukuda Yasutaka, Inano Tadaaki, Ochiai Tomonori, Shirane Shuichi, Edahiro Yoko, Araki Marito, Ando Miki, Komatsu Norio

Abstract excerpt

OBJECTIVES: Hemorrhagic events are a rare but potentially fatal complication in patients with polycythemia vera (PV). METHODS: We analyzed the characteristics of hemorrhagic events in 267 patients with PV. RESULTS: A median follow-up of 4.8 years revealed that 23 (8.6%) hemorrhagic events occurred. Significantly more hemorrhagic events occurred in younger patients aged below 60 years (n = 72) than in older...

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PMID: 39545588
DOI: 10.1080/16078454.2024.2427905

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