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Article

Modulator-refractory cystic fibrosis: Defining the scope and challenges of an emerging at-risk population.

Therapeutic advances in respiratory disease - 1 Jan 2000

Somerville Lindsay, Borish Larry, Noth Imre, Albon Dana

Abstract excerpt

Cystic fibrosis (CF) causes life-shortening respiratory and systemic disease due to dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. Highly effective modulator therapies (HEMT) improve the lives of many people with cystic fibrosis (PwCF) by correcting the structure and function of the defective CFTR channel at the molecular level. Despite these advancements, a subset...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39543951
DOI: 10.1177/17534666241297877
PMCID: PMC11565698

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Modulator-refractory cystic fibrosis: Defining the scope and challenges of an emerging at-risk population.PMID 39543951Read ↗

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