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Cystic Fibrosis Modulator Therapies.

Annual review of medicine - 27 Jan 2023

Jia Shijing, Taylor-Cousar Jennifer L

Abstract excerpt

Cystic fibrosis (CF) is an inherited multisystemic disease that can cause progressive bronchiectasis, pancreatic endocrine and exocrine insufficiency, distal intestinal obstruction syndrome, liver dysfunction, and other disorders. Traditional therapies focused on the treatment or prevention of damage to each organ system with incremental modalities such as nebulized medications for the lungs, insulin for...

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PMID: 35973718
DOI: 10.1146/annurev-med-042921-021447

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