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Article

Impact of PNPLA3 in Lean Individuals and in Cryptogenic Steatotic Liver Disease.

Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2025

Seko Yuya, Lin Huapeng, Wong Vincent Wai-Sun, Okanoue Takeshi

Abstract excerpt

BACKGROUND: Although metabolic dysfunction-associated steatotic liver disease (MASLD) is strongly associated with obesity, around 20% of individuals with hepatic steatosis may nonetheless have normal body mass index, a condition often referred to as lean nonalcoholic fatty liver disease (NAFLD). Under the new nomenclature and definition of MASLD, lean NAFLD can be further divided into lean MASLD (when there is...

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Source

Identifiers

PMID: 39540675
DOI: 10.1111/liv.16164

Genes

PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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