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Article

The Interaction of Polygenic Susceptibility to Stress and Childhood Adversity Dimensions Predicts Longitudinal Trajectories of Stress-Sensitivity.

Stress and health : journal of the International Society for the Investigation of Stress - 1 Dec 2024

Barrantes-Vidal N, Gizdic A, Torrecilla P, Mas-Bermejo P, Sheinbaum T, Papiol S, Lafit G, Myin-Germeys I, Rosa A, Kwapil T R

Abstract excerpt

Stress-sensitivity (SS) is considered a psychobiological trait possibly resulting from the interaction of genetic and environmental factors (GxE). This study examined whether the interaction of SS-related genetic markers with interview-based dimensions of childhood adversity predicted longitudinal trajectories of low versus high SS. Participants were nonclinically-ascertained young adults comprising normative and...

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Identifiers

PMID: 39540673
DOI: 10.1002/smi.3499
PMCID: PMC11636442

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