Genetic Differences in Reactivity to the Environment Impact Psychotic-Like and Affective Reactivity in Daily Life.

doi:10.1093/schbul/sbad162

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Article

Genetic Differences in Reactivity to the Environment Impact Psychotic-Like and Affective Reactivity in Daily Life.

Schizophrenia bulletin - 4 Mar 2025

Barrantes-Vidal Neus, Torrecilla Pilar, Mas-Bermejo Patricia, Papiol Sergi, Bakermans-Kranenburg Marian J, Rosa Araceli, Kwapil Thomas R

Abstract excerpt

BACKGROUND AND HYPOTHESIS: Consistent with diathesis-stress models, psychosis research has focused on genetic moderation of adverse environmental exposures. In contrast, the Differential Susceptibility (DS) model suggests that the same genetic variants that increase risk-inducing effects of adverse experiences also enhance beneficial effects from positive experiences. This study examined whether individuals with...

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Topics

Humans
Male
Female
Adult
Gene-Environment Interaction
Psychotic Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Paranoid Disorders

Affect

Young Adult

Ecological Momentary Assessment

Genetic Predisposition to Disease

Middle Aged

Multifactorial Inheritance

Adolescent

Schizotypal Personality Disorder

Stress, Psychological

Source

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Identifiers

PMID: 40037823
DOI: 10.1093/schbul/sbad162
PMCID: PMC11879516

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