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Article

VEGFC Overexpression in Kidney Progenitor Cells Is a Model of Renal Lymphangiectasia-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2025

Donnan Michael D, Deb Dilip K, Dalal Vidhi, David Valentin, Procissi Daniele, Quaggin Susan E

Abstract excerpt

BACKGROUND: Lymphangiogenesis is believed to be a protective response in the setting of multiple forms of kidney injury and mitigates the progression of interstitial fibrosis. To augment this protective response, promoting kidney lymphangiogenesis is being investigated as a potential treatment to slow the progression of kidney disease. As injury-related lymphangiogenesis is driven by signaling from the receptor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 39540281
DOI: 10.1161/ATVBAHA.124.319743
PMCID: PMC11668614

Genes

EMCN
VEGFC
LYVE1
PDPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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