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Activation of pericytes

17 Nov 2012

Abstract excerpt

PURPOSE OF REVIEW: Pathological deposition of fibrous matrix in organs is a major problem and contributes to as many as 45% of all natural deaths. Chronic kidney disease affects 8% of the US population, and is characterized by fibrotic processes. It frequently progresses to organ failure and is a major cause of cardiovascular death; yet it lacks therapies. Understanding the pathological mechanisms of fibrosis in...

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PMID: 23196325
DOI: 10.1097/bor.0b013e32835b656b

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