Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Balanced regulation of ROS production and inflammasome activation in preventing early development of colorectal cancer

10 Nov 2024

Abstract excerpt

Reactive oxygen species (ROS) production and inflammasome activation are the key components of the innate immune response to microbial infection and sterile insults. ROS are at the intersection of inflammation and immunity during cancer development. Balanced regulation of ROS production and inflammasome activation serves as the central hub of innate immunity, determining whether a cell will survive or undergo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers in Disease Mechanisms
Share to Inflammasome and immune disorders
Share to Lipid metabolism and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39523732
DOI: 10.1111/imr.13417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Balanced regulation of ROS production and inflammasome activation in preventing early development of colorectal cancerPMID 39523732Read ↗

NLRC4, inflammation and colorectal cancer (Review).Semantic proximity Read ↗

NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2.Semantic proximity Read ↗

Inflammasomes and Colorectal CancerSemantic proximity Read ↗

Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients With Crohn's Disease.Semantic proximity Read ↗

Inflammasomes Are Influenced by Epigenetic and Autophagy Mechanisms in Colorectal Cancer SignalingSemantic proximity Read ↗

Epithelial CRL4 DCAF2 is critical for maintaining intestinal homeostasis by regulating the proliferation and repair of intestinal epithelial cellsSemantic proximity Read ↗

Autophagy in colitis-associated colon cancer: exploring its potential role in reducing initiation and preventing IBD-Related CAC developmentSemantic proximity Read ↗

Reactive oxygen species and colorectal cancer.Semantic proximity Read ↗

Toll‐like receptor 4 regulates spontaneous intestinal tumorigenesis by up‐regulating IL‐6 and GM‐CSFSemantic proximity Read ↗

The Role of Mitochondria Dysfunction in Inflammatory Bowel Diseases and Colorectal CancerSemantic proximity Read ↗

The E3 ubiquitin ligase RNF186 and RNF186 risk variants regulate innate receptor-induced outcomes.Semantic proximity Read ↗

Beneficial and Detrimental Roles of NLRs in CarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.