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DNA methylation classifier to diagnose pancreatic ductal adenocarcinoma metastases from different anatomical sites

10 Nov 2024

Abstract excerpt

BACKGROUND: We have recently constructed a DNA methylation classifier that can discriminate between pancreatic ductal adenocarcinoma (PAAD) liver metastasis and intrahepatic cholangiocarcinoma (iCCA) with high accuracy (PAAD-iCCA-Classifier). PAAD is one of the leading causes of cancer of unknown primary and diagnosis is based on exclusion of other malignancies. Therefore, our focus was to investigate whether the...

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PMID: 39523345
DOI: 10.1186/s13148-024-01768-x

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