Article
DNA methylation profile to aid in the diagnosis of pancreatic ductal adenocarcinoma and its role in disease progression
3 Sept 2025
Abstract excerpt
There is no immunohistochemical or molecular marker to confirm the histologic diagnosis of pancreatic ductal adenocarcinoma (PDAC). This is particularly important in a scenario of unknown primary. Molecularly, PDAC is characterized by a limited set of driver mutations, and new predictive and prognostic markers are needed to guide novel therapies. Recent data show that DNA methylation profiles combined with...
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