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Article

Phenotypic diversity of Bordetella pertussis against Trimethoprim/Sulphamethoxazole in vitro tests.

Diagnostic microbiology and infectious disease - 1 Jan 2025

Hu Yahong, Zhai Xinyi, Yuan Lin, Du Qianqian, Yao Kaihu

Abstract excerpt

BACKGROUND: Trimethoprim/sulfamethoxazole (TMP/SMZ), traditionally a second-line drug, is now proposed as the primary alternative treatment for macrolide-resistant Bordetella pertussis (B.pertussis). Thus, there is an urgent need to evaluate the phenotypic profile of B. pertussis regarding susceptibility to TMP/SMZ. METHODS: Kirby-Bauer (KB) disk diffusion methods and E-test strips were employed to assess the in...

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PMID: 39522362
DOI: 10.1016/j.diagmicrobio.2024.116597

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