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Polyribonucleotide phosphorylase is overexpressed in hepatocellular cancer, promoting epithelial phenotype maintenance and tumor progression.

Pathology, research and practice - 1 Dec 2024

Revert-Ros Francisco, Ventura Ignacio, Prieto-Ruiz Jesús A, Giner-Moreno Eduardo, Pérez-Cervera Ángela, Pérez-Rojas Judith, Revert Fernando, Hernández-Andreu José Miguel

Abstract excerpt

Liver cancer, particularly hepatocellular carcinoma (HCC), is a major global health challenge, largely associated with cirrhosis caused by various factors. Prognosis is often guided by molecular and histological classifications. In this study, expression of Polyribonucleotide Phosphorylase (PNPT1) in HCC was investigated to better understand its role in tumor behavior and patient outcomes. The expression of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39522317
DOI: 10.1016/j.prp.2024.155713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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