Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SNRPB/CCNB1 axis promotes hepatocellular carcinoma progression and cisplatin resistance through enhancing lipid metabolism reprogramming

18 Jul 2025

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality globally, significantly impacting worldwide health. Hence, identifying key molecular drivers of HCC progression is crucial for enhancing treatment options and prognostic methods. This study explores the function of Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB) in HCC, unveiling critical pathways that affect the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Ferroptosis and cancer prognosis
Share to FOXO transcription factor regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40682115
DOI: 10.1186/s13046-025-03463-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SNRPB/CCNB1 axis promotes hepatocellular carcinoma progression and cisplatin resistance through enhancing lipid metabolism reprogrammingPMID 40682115Read ↗

The oncogenic role of SNRPB in human tumors: A pan-cancer analysisSemantic proximity Read ↗

Unveiling the Hidden Role of SNRPB2 in HCC: A Promising Target for TherapySemantic proximity Read ↗

Comprehensive transcriptomic analysis of hepatocellular Carcinoma: Uncovering shared and unique molecular signatures across diverse etiologiesSemantic proximity Read ↗

N6-methyladenosine (m6A) RNA methylation regulator SNRPC is a prognostic biomarker and is correlated with immunotherapy in hepatocellular carcinomaSemantic proximity Read ↗

Comprehensive analysis of the expression and prognostic value for SNRP members in hepatocellular carcinomaSemantic proximity Read ↗

Deciphering the Oncogenic Landscape of Hepatocytes Through Integrated Single‐Nucleus and Bulk RNA‐Seq of Hepatocellular CarcinomaSemantic proximity Read ↗

The landscape of Hepatocellular Carcinoma and Tumor-associated Telocytes Integrated Single-nucleus RNA Sequence and Transcriptomics TechnologySemantic proximity Read ↗

Single-Cell RNA Sequencing Combined with Single-Cell Genome-Wide Association Study Identifies SF3B4 as a hub Gene in Hepatocellular Carcinoma ProgressionSemantic proximity Read ↗

Polyribonucleotide phosphorylase is overexpressed in hepatocellular cancer, promoting epithelial phenotype maintenance and tumor progression.Semantic proximity Read ↗

A novel lncRNA RP11-386G11.10 reprograms lipid metabolism to promote hepatocellular carcinoma progressionSemantic proximity Read ↗

Tilte：SNRPA may mediate transcription and splicing of genesassociated with HCC via binding special RNAsSemantic proximity Read ↗

A Novel lncRNA-Mediated Signaling Axis Governs Cancer Stemness and Splicing Reprogramming in Hepatocellular Carcinoma with Therapeutic PotentialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.