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Article

The Causal Relationship Between Choline Metabolites and Acute Acalculous Cholecystitis: Identifying ABCG8 as Colocalized Gene.

Nutrients - 22 Oct 2024

Gao Yuntong, Mao Kun, Yang Congying, Wang Xisu, Liu Shixuan, Ma Zimeng, Zhai Qi, Shi Liang, Wu Qian, Zhang Tianxiao

Abstract excerpt

BACKGROUND: Acute acalculous cholecystitis (AAC) is a type of cholecystitis with high mortality rate while its pathogenesis remains complex. Choline is one of the essential nutrients and is related to several diseases. This study aimed to explore the causal relationship between choline metabolites and AAC and its potential mechanisms. METHODS: This research utilized the two-sample Mendelian randomization method...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 8
Share to Choline

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Lipoproteins, LDL

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Share to Phosphatidylcholines

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Identifiers

PMID: 39519421
DOI: 10.3390/nu16213588
PMCID: PMC11547454

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