Article
Genomics Study of Gastric Cancer and Its Molecular Subtypes.
Advances in experimental medicine and biology - 1 Jan 2000
Yuen Siu Tsan, Leung Suet Yi
Abstract excerpt
Gastric cancer is a heterogeneous disease encompassing diverse morphological (intestinal versus diffuse) and molecular subtypes (MSI, EBV, TP53 mutation). Recent advances in genomic technology have led to an improved understanding of the driver gene mutational profile, gene expression, and epigenetic alterations that underlie each of the subgroups, with therapeutic implications in some of these alterations. There...
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