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Phthalates are detected in the follicular fluid of adolescents and oocyte donors with associated changes in the cumulus cell transcriptome

7 Nov 2024

Abstract excerpt

OBJECTIVE: To investigate the follicular fluid (FF) phthalate levels in adolescents undergoing fertility preservation compared with oocyte donors and explore its association with ovarian reserve and cumulus cell (CC) gene expression. DESIGN: Retrospective study and molecular analysis of CCs and FF. SUBJECTS: Adolescents (n = 20, 16.7 ± 0.6 years) undergoing fertility preservation and oocyte donors (n = 24, 26.2 ±...

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PMID: 39515754
DOI: 10.1016/j.xfss.2024.10.009

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