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Article

Endocrine-disrupting chemicals in human follicular fluid impair in vitro oocyte developmental competence

20 Jan 2012

Abstract excerpt

BACKGROUND: Increased global industrial activity has exposed humans to a wide variety of chemical substances some of which, called 'endocrine-disrupting chemicals' (EDCs) or 'endocrine disruptors', can disrupt the endocrine system in the body. The ovarian follicle is a very fragile micro-environment where interactions between hormones, growth factors, the oocyte and its surrounding somatic cells are essential to...

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PMID: 22267834
DOI: 10.1093/humrep/der448

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