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Preconception urinary phthalate concentrations and sperm DNA methylation profiles among men undergoing IVF treatment: a cross-sectional study

9 Aug 2017

Abstract excerpt

STUDY QUESTION: Are preconception phthalate and phthalate replacements associated with sperm differentially methylated regions (DMRs) among men undergoing IVF? SUMMARY ANSWER: Ten phthalate metabolites were associated with 131 sperm DMRs that were enriched in genes related to growth and development, cell movement and cytoskeleton structure. WHAT IS KNOWN ALREADY: Several phthalate compounds and their metabolites...

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Effects and risks of endocrine disrupting chemicals
Folate and B Vitamins Research
Pharmacological Effects and Toxicity Studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29024969
DOI: 10.1093/humrep/dex283

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