Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ZIP7 contributes to the pathogenesis of diabetic cardiomyopathy by suppressing mitophagy in mouse hearts

7 Nov 2024

Abstract excerpt

Although the exact role of mitophagy in the pathogenesis of diabetic cardiomyopathy (DCM) caused by type 2 diabetes mellitus (T2DM) remains controversial, recent studies revealed inhibition of mitophagy exacerbates cardiac injury in DCM. The zinc transporter ZIP7 has been reported to be upregulated by high glucose in cardiomyocytes and ZIP7 upregulation leads to inhibition of mitophagy in mouse hearts in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cardiomyopathy and Myosin Studies
Share to Cardiovascular Function and Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39511569
DOI: 10.1186/s12933-024-02499-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ZIP7 contributes to the pathogenesis of diabetic cardiomyopathy by suppressing mitophagy in mouse heartsPMID 39511569Read ↗

Mitophagy in Diabetic Cardiomyopathy: Roles and MechanismsSemantic proximity Read ↗

The Role of Mitochondrial Abnormalities in Diabetic CardiomyopathySemantic proximity Read ↗

Important regulatory role of mitophagy in diabetic microvascular complicationsSemantic proximity Read ↗

USP7 aggravates diabetic cardiomyopathy by stabilizing Keap1 to govern cardiac oxidative stress and pyroptosisSemantic proximity Read ↗

Cardiomyocyte-specific Txnip C247S mutation improves left ventricular functional reserve in streptozotocin-induced diabetic mice.Semantic proximity Read ↗

Sirt3 deficiency exacerbates diabetic cardiac dysfunction: Role of Foxo3A-Parkin-mediated mitophagySemantic proximity Read ↗

From bench to bedside: targeting ferroptosis and mitochondrial damage in the treatment of diabetic cardiomyopathySemantic proximity Read ↗

Phosphatase and tensin homolog‐induced putative kinase 1 and Parkin in diabetic heart: Role of mitophagySemantic proximity Read ↗

Diabetes cardiomyopathy: targeted regulation of mitochondrial dysfunction and therapeutic potential of plant secondary metabolitesSemantic proximity Read ↗

Mitophagy Regulation Following Myocardial InfarctionSemantic proximity Read ↗

Novel Insights Into the Pathogenesis of Diabetic Cardiomyopathy and Pharmacological StrategiesSemantic proximity Read ↗

FOXO3a-dependent PARKIN negatively regulates cardiac hypertrophy by restoring mitophagySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.