Article
Phosphatase and tensin homolog‐induced putative kinase 1 and Parkin in diabetic heart: Role of mitophagy
16 Oct 2014
Abstract excerpt
Diabetes is an independent risk factor for cardiovascular morbidity and mortality. Diabetes-associated cardiac pathophysiology is recognized to be due to reasons including metabolic consequences on the myocardium. The heart is a highly energy-demanding tissue, with mitochondria supplying over 90% of adenosine triphosphate. The involvement of mitochondrial dysfunction in diabetes-related cardiac pathogenesis has...
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