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Article

YAP1 and WWTR1 are required for murine pregnancy initiation.

Reproduction (Cambridge, England) - 1 Jan 2025

Moldovan Genna E, Massri Noura, Vegter Erin L, Pauneto-Delgado Ivonne N, Burns Gregory W, Joshi Niraj, Gu Bin, Arora Ripla, Fazleabas Asgerally T

Abstract excerpt

In brief: The HIPPO signaling effectors YAP1 and WWTR1 are required for murine pregnancy initiation, and mutation of these factors compromises the decidualization response and overall pregnancy success. Abstract: Endometrial stromal cell decidualization is required for pregnancy success. Although this process is integral to fertility, many of the intricate molecular mechanisms contributing to decidualization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39503541
DOI: 10.1530/REP-24-0355
PMCID: PMC11874952

Genes

WWTR1
YAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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