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Article

The role of circulating cytokines in heart failure: a bidirectional, two-sample Mendelian randomization study

22 Oct 2024

Abstract excerpt

Background Cytokines play a pivotal role in the progression of heart failure (HF) by modulating inflammatory responses, promoting vasoconstriction, and facilitating endothelial injury. However, it is now difficult to distinguish the causal relationship between HF and cytokines in observational studies. Mendelian randomization (MR) analyses of cytokines probably could enhance our comprehension to the underlying...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 39502198
DOI: 10.3389/fcvm.2024.1332015

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