Article
Allele-specific micro-RNA-mediated regulation of ADAM33 in childhood allergic asthma.
Respirology (Carlton, Vic.) - 1 Feb 2025
Wen Xiang, Zhou Juan, Fang Heping, Li Juan, Wang Run, Zeng Dan, Xie Xiaohong, Deng Yu, Ren Luo, Liu Enmei
Abstract excerpt
BACKGROUND AND OBJECTIVE: A disintegrin and metalloprotease 33 (ADAM33) is associated with asthma susceptibility, and its genetic variations impact susceptibility and disease severity. However, the mechanisms remain unclear. This study aimed to investigate ADAM33 single nucleotide polymorphisms (SNPs) in childhood asthma susceptibility and explore their regulatory mechanisms. METHODS: Eleven selected SNPs in...
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