Reliability of Genetic Alterations in Predicting Ceftriaxone Resistance in Neisseria gonorrhoeae Globally.

doi:10.1128/spectrum.02065-21

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Article

Reliability of Genetic Alterations in Predicting Ceftriaxone Resistance in Neisseria gonorrhoeae Globally.

Microbiology spectrum - 27 Apr 2022

Lin Eric Yu, Adamson Paul C, Ha Sung-Min, Klausner Jeffrey D

Abstract excerpt

Antimicrobial resistance in N. gonorrhoeae is increasing globally, and ceftriaxone is the recommended treatment for empirical therapy in most settings. Developing molecular assays to detect decreased ceftriaxone susceptibility is critical. Using PathogenWatch, a public database of N. gonorrhoeae genomes, antibiotic susceptibility data and DNA sequences of different genes associated with ceftriaxone resistance...

Topics

Anti-Bacterial Agents
Ceftriaxone
Drug Resistance, Bacterial
Genetic Markers
Gonorrhea
Humans
Microbial Sensitivity Tests
Mutation
Neisseria gonorrhoeae
Reproducibility of Results

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PMID: 35348352
DOI: 10.1128/spectrum.02065-21
PMCID: PMC9045316

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