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Article

Genetic polymorphism of merozoite surface protein 1 and merozoite surface protein 2 in the Vietnam Plasmodium falciparum population.

BMC infectious diseases - 28 Oct 2024

Võ Tuấn Cường, Lê Hương Giang, Kang Jung-Mi, Trinh Nguyen Thi Minh, Quang Huynh Hong, Na Byoung-Kuk

Abstract excerpt

BACKGROUND: Plasmodium falciparum merozoite surface proteins 1 (PfMSP1) and 2 (PfMSP2) are potential candidates for malaria vaccine development. However, the genetic diversity of these genes in the global P. falciparum population presents a significant challenge in developing an effective vaccine. Hence, understanding the genetic diversity and evolutionary trends in the global P. falciparum population is crucial....

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Identifiers

PMID: 39468465
DOI: 10.1186/s12879-024-10116-6
PMCID: PMC11520470

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