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Impaired Kynurenine Pathway in Inflammatory Bowel Disease

15 Oct 2024

Abstract excerpt

Background/Objectives: Inflammatory bowel diseases primarily encompass Crohn’s disease and ulcerative colitis. Insufficient levels of tryptophan cause an imbalance in the gut microbiota, leading to inflammation in the gastrointestinal tract. The main catabolic pathway of tryptophan is the kynurenine pathway. Our study aims to evaluate serum tryptophan, the kynurenine pathway, and oxidative stress parameters,...

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PMID: 39458097
DOI: 10.3390/jcm13206147

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