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The Kynurenine Pathway and Polycystic Ovary Syndrome: Inflammation as a Common Denominator

1 Jan 2022

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a complex metabolic disorder commonly seen in females of reproductive age. The pathophysiology of PCOS is multifactorial and includes dysfunction in ovarian steroidogenesis and folliculogenesis, impaired gonadotropin levels, insulin resistance, gut microbiota imbalance, genetic predisposition, and lifestyle preferences. Low-grade inflammatory conditions such as obesity and...

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PMID: 35620306
DOI: 10.1177/11786469221099214

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