Article
Targeting mitochondria: a novel approach for treating platinum-resistant ovarian cancer.
Journal of translational medicine - 25 Oct 2024
Cui Xin, Xu Juan, Jia Xuemei
Abstract excerpt
Ovarian cancer is a prevalent gynecologic malignancy with the second-highest mortality rate among gynecologic malignancies. Platinum-based chemotherapy is the first-line treatment for ovarian cancer; however, a majority of patients with ovarian cancer experience relapse and develop platinum resistance following initial treatment. Despite extensive research on the mechanisms of platinum resistance at the nuclear...
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