Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline genetic variants in a case of familial cancer: RAD51D and four other co-segregated variants.

Journal of genetics - 1 Jan 2024

Biswas Shristi, Manekar Swati, Kantharia Shehnaz, Bakshi Sonal

Abstract excerpt

Cancer is a multifactorial, multi-step process of pathogenesis; however, in the case of familial cancers, genetic aetiology can play a significant role. Identifying genetic variants in cancer patients having a strong family history of cancer as well as their unaffected blood relatives can unravel their role in predisposition to cancer. Here, we report the findings of whole-exome sequencing in a patient (77/F)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to DNA-Binding Proteins
Share to Exome Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Hereditary Breast and Ovarian Cancer Syndrome

Share to High-Throughput Nucleotide Sequencing

Share to Pedigree

Source

Identifiers

PMID: 39445568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline genetic variants in a case of familial cancer: RAD51D and four other co-segregated variants.PMID 39445568Read ↗

A decade of RAD51C/D: Germline pathogenic variants and their phenotypic landscapeSemantic proximity Read ↗

A decade of RAD51C and RAD51D germline variants in cancer.Semantic proximity Read ↗

Rare Germline Genetic Variants and the Risks of Epithelial Ovarian CancerSemantic proximity Read ↗

Expanding cancer predisposition genes with ultra-rare cancer-exclusive human variations.Semantic proximity Read ↗

Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases.Semantic proximity Read ↗

Expanding cancer predisposition genes with ultra-rare cancer-exclusive human variationsSemantic proximity Read ↗

Pathogenic variants in affected and unaffected individuals from Indonesian familial cancer: a multigene panel analysis.Semantic proximity Read ↗

Cancer genetics-one family at a time.Semantic proximity Read ↗

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.Semantic proximity Read ↗

Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer.Semantic proximity Read ↗

The prospect of discovering new biomarkers for ovarian cancer based on current knowledge of susceptibility loci and genetic variation (Review).Semantic proximity Read ↗

Four cancer cases with pathological germline variant RAD51D c.270_271dup.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.