Cancer genetics-one family at a time.

Abstract excerpt

This article is a distillation and extension of some of themes I presented as a lecture to the Canadian Society of Clinical Investigation meeting in Banff in 2019. I emphasize the important role that investigation of a few key families seen in our clinic (sometimes as few as one) can play in cancer genetic discovery. I present the work both thematically and chronologically, demonstrating how clinical observation,...

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