Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline variants of homology-directed repair or mismatch repair genes in cervical cancer.

International journal of cancer - 15 Feb 2025

Kokemüller Lara, Ramachandran Dhanya, Schürmann Peter, Geffers Robert, Jentschke Matthias, Böhmer Gerd, Strauß Hans-Georg, Hirchenhain Christine, Schmidmayr Monika, Müller Florian, Fasching Peter A, Luyten Alexander, Häfner Norman, Hillemanns Peter, Dörk Thilo

Abstract excerpt

While cervical cancer is associated with a persistent human papillomavirus (HPV) infection, the progression to cancer is influenced by genomic risk factors that have remained largely obscure. Pathogenic variants in genes of the homology-directed repair (HDR) or mismatch repair (MMR) are known to predispose to diverse tumour entities including breast and ovarian cancer (HDR) or colon and endometrial cancer (MMR)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

Share to Germ-Line Mutation

Share to High-Throughput Nucleotide Sequencing

Share to Papillomavirus Infections

Share to Recombinational DNA Repair

Share to Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 39440754
DOI: 10.1002/ijc.35221
PMCID: PMC11661519

Genes

BARD1
BRCA1
BRCA2
BRIP1
FANCM
MSH6
RAD51D
SLX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline variants of homology-directed repair or mismatch repair genes in cervical cancer.PMID 39440754Read ↗

Germline susceptibility variants impact clinical outcome and therapeutic strategies for stage III colorectal cancerSemantic proximity Read ↗

A decade of RAD51C and RAD51D germline variants in cancer.Semantic proximity Read ↗

Rare Germline Genetic Variants and the Risks of Epithelial Ovarian CancerSemantic proximity Read ↗

Germline Variants in Proto-Oncogenes and Tumor Suppressor Genes in Women with Cervical CancerSemantic proximity Read ↗

Multigene panel analysis identified germline mutations of DNA repair genes in breast and ovarian cancerSemantic proximity Read ↗

A decade of RAD51C/D: Germline pathogenic variants and their phenotypic landscapeSemantic proximity Read ↗

UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2.Semantic proximity Read ↗

Genomic Risk Factors for Cervical CancerSemantic proximity Read ↗

Mutations of TP53 and genes related to homologous recombination repair in breast cancer with germline BRCA1/2 mutationsSemantic proximity Read ↗

Germline DNA Damage Repair Gene Alterations in Patients with Metachronous Breast and Colorectal Cancer.Semantic proximity Read ↗

Emerging role of mutations in epigenetic regulators including MLL2 derived from The Cancer Genome Atlas for cervical cancer.Semantic proximity Read ↗

Genomic Risk Factors for Cervical CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.