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Article

Expression and function of interferon lambda receptor 1 variants.

FEBS letters - 1 Feb 2025

Novotny Laura A, Meissner Eric G

Abstract excerpt

Lambda interferons (IFNLs) provide critical host defense against pathogens encountered at mucosal surfaces. In humans, IFNL signaling is regulated in part by low and cell-type restricted expression of the lambda interferon receptor 1 protein with expression restricted primarily to epithelial cells located at mucosal surfaces. This review will examine the evidence suggesting a role for IFNLR1 transcriptional...

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Source

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Identifiers

PMID: 39435588
DOI: 10.1002/1873-3468.15041
PMCID: PMC11850208

Genes

IFNLR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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