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Article

Genetically predicted hypothyroidism, thyroid hormone treatment, and the risk of cardiovascular diseases: a mendelian randomization study.

BMC cardiovascular disorders - 10 Sept 2024

Zhang Shuaidan, Yu Hangtian, Zhao Yan, Gong Angwei, Guan Chengjian, Chen Shuchen, Xiao Bing, Lu Jingchao

Abstract excerpt

BACKGROUND: In this study, we explored the impact of hypothyroidism and thyroid hormone replacement therapy on the risk of developing cardiovascular diseases, including myocardial infarction, heart failure, and cardiac death, via Mendelian randomization analysis. METHODS: Genetic instrumental variables related to hypothyroidism, levothyroxine treatment (refer to Participants were taking the medication...

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Identifiers

PMID: 39256710
DOI: 10.1186/s12872-024-04132-2
PMCID: PMC11386095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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