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Intraspecies Transcriptional Profiling Reveals Key Regulators of Candida albicans Pathogenic Traits.

mBio - 20 Apr 2021

Wang Joshua M, Woodruff Andrew L, Dunn Matthew J, Fillinger Robert J, Bennett Richard J, Anderson Matthew Z

Abstract excerpt

The human commensal and opportunistic fungal pathogen Candida albicans displays extensive genetic and phenotypic variation across clinical isolates. Here, we performed RNA sequencing on 21 well-characterized isolates to examine how genetic variation contributes to gene expression differences and to link these differences to phenotypic traits. C. albicans adapts primarily through clonal evolution, and yet...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33879584
DOI: 10.1128/mBio.00586-21
PMCID: PMC8092256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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