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Article

TMEM175 plays a crucial role in osteoblast differentiation by regulating lysosomal function and autophagy.

Molecules and cells - 1 Nov 2024

Lee Seung Hye, Jang Ji Sun, Mo Shenzheng, Kim Hong-Hee

Abstract excerpt

Bone provides structural support, enables movement, protects internal organs, regulates calcium and phosphorus levels, and contains bone marrow essential for hematopoiesis. Osteoblasts are specialized cells responsible for bone formation through the secretion of extracellular matrix components. Transmembrane protein 175 (TMEM175), which functions as an endosomal/lysosomal K+ channel and a lysosomal H+ channel,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39426687
DOI: 10.1016/j.mocell.2024.100127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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