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Article

Three functional polymorphisms in CCDC170 were associated with osteoporosis phenotype.

Biology open - 15 Apr 2021

Liu Xinhong, Li Yu-Gang, Tan Fang, Liu Jia, Yi Ruokun, Zhao Xin

Abstract excerpt

MicroRNAs (miRNAs) play essential roles in regulating bone formation and homeostasis. Genomic variations within miRNA target sites may therefore be important sources of genetic differences in osteoporosis risk. The function of CCDC170 in bone biology is still unclear. To verify the function of CCDC170, we knocked down CCDC170 in cells and mice and searched for miRNA recognition sites within CCDC170 using the...

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Identifiers

PMID: 33785515
DOI: 10.1242/bio.050930
PMCID: PMC8061906

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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